Endocrinology and Toxicology Research Laboratory

              Our current research activities address specific concerns on the impacts of environmental contaminants on aquatic ecosystems. The laboratory is actively involved in the quantitative analysis of chemical contaminants in various tissue matrices using both conventional and modern techniques. We have identified the role of certain xenobiotics in the antioxidant defense system, and the molecular mechanism involved in the impairment of reproductive functions in fish. The role of some endocrine disruptors like phthalate plasticizers, chlordecone, fullerene C₆₀ nanomaterials, and triclosan in the decline of sperm count mediated through the hypothalamic-pituitary-gonadal axis contributed to the reduced fish population. We also apply fish genetics in combination with molecular, biochemical, and cytological approaches to address fundamental questions regarding the environmental stressors induced oxidative stress. Our research applies several fish species such as orange/ red chromide (Pseudetroplus maculatus), tilapia (Oreochromis mossambicus), climbing perch (Anabas testudineus), and mosquitofish (Gambusia affinis) as laboratory models.

                                                                Ph.D. SCHOLARS (ONGOING)

	NIKHIL JOHN M.Sc., Email: This email address is being protected from spambots. You need JavaScript enabled to view it. UGC-JRF Title of Thesis:  Influence of diazepam, an antipsychotic drug, on the stress parameters in the mosquitofish (Baird and Girard, 1853)
	REEHA MASHIRIN K. M. Sc., Email: This email address is being protected from spambots. You need JavaScript enabled to view it. UGC-JRF Title of Thesis: Impacts of polystyrene microplastics on hepatic biotransformation, gut microbial and endocrine dysfunctions in the freshwater fish Anabas testudineus (Bloch, 1792)
	MANEESHA P. M. Sc., Email: This email address is being protected from spambots. You need JavaScript enabled to view it. JRF-UGC Tiltle of Thesis: Stress response of the freshwater fish Oreochromis mossambicus (Peters, 1852) exposed to a synthetic musk, galaxolide

M. Phil SCHOLARS (ONGOING)

Neetha Ramesh  M.Sc., B. Ed.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.     Area of Research:    Toxicology

Ph. D AWARDED

			Dr. ASIFA K. P.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Date of award: 21 November, 2018   Title of Thesis:    Evaluation of the effect of an endocrine disrupting chemical, chlordecone, in the reproductive and non-reproductive    tissues of the  cichlid fish, Pseudetroplus maculatus (Bloch, 1795)   Current Position:    Higher Secondar Teacher, Govt. Higher Secondary School Koduvally, Calicut, Kerala
			Dr. VIDYA BALAKRISHNAN P. V.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Date of award: 05 July, 2019      Title of Thesis:    Effects of selected nanoparticles on the freshwater fish, Oreochromis mossambicus (Peters, 1852)   Current Position:    Guest Faculty, Department of Zoology, Government Arts and Science College for Women, Malappuram, Kerala
			Dr. SUMI N.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Date of award: 09 July, 2020     Title of Thesis:    Assessment of fullerene C60, a carbon nanomaterial, induced toxic response in the freshwater fish, Anabas     testudineus (Bloch, 1792)   Current Position:    Post-Doctoral Fellow, Department of Environmental Toxicology, College of agricultural and Environmental Sciences, University of California, Davis
			Dr. REVATHY V.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Date of award: 11 August, 2020     Title of Thesis:    Toxic effects of the phthalate plasticizers in the freshwater fish, Oreochromis mossambicus (Peters, 1852)   Current Position:   Livestock Inspector, Malappuram, Kerala.
			Dr. RAIBEEMOL K. P.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Date of award: 12 November, 2020     Title of Thesis:    Biochemical and immunotoxicological effects of chlorpyrifos in the freshwater fish Pseudetroplus maculatus (Bloch,    1795)   Current Position:
			Dr. PRIYATHA C. V.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Date of award: 18 March, 2022     Title of Thesis:    Evaluation of triclosan-induced reproductive toxicity in the freshwater fish Anabas testudineus (Bloch 1792)    Current Position:

                                                                          M. Phil. AWARDED

			N. V. SREEDEVI   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Degree Awarded: December, 2013   Title of Thesis:  Genotoxic potential and biochemical effects of octylphenol in hepatic mitochondrial fractions of freshwater fish, Oreochromis mossambicus (Peters, 1852)						PRIYATHA C. V.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Degree Awarded: September, 2016   Title of Thesis:  In vitro exposure to triclosan induces oxidative stress in epididymal sperm of goat, Capra hircus L. (1758)
			SAJLA K.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Degree Awarded: August, 2019   Title of Thesis:  Evaluation of dibutyl phthalate (DBP)-induced ovarian toxicity in the freshwater fish, Pseudetroplus maculatus (Bloch, 1795)						SRUTHI M.   Email: This email address is being protected from spambots. You need JavaScript enabled to view it.   Degree Awarded: August, 2020   Title of Thesis:  Evidence of testicular toxicity induced by sublethal exposure of dibutyl phthalate in the freshwater fish, Pseudetroplus maculatus (Bloch, 1795)
			P. K.  This email address is being protected from spambots. You need JavaScript enabled to view it. Email: This email address is being protected from spambots. You need JavaScript enabled to view it. Degree awarded: 2022 . Title of Thesis:   Triclosan at environmental concentration alters the hepatic antioxidant defence system in the fish, Anabas testudineus (Bloch, 1792)						SANOOPA C. P. Email: This email address is being protected from spambots. You need JavaScript enabled to view it.  Degree awarded: 2022  Title of Thesis:    Sublethal hepato-toxic effects and biotransformation response in the freshwater fish, Oreochromis mossambicus (Peters, 1852) exposed to silicon dioxide nanoparticles